This is a selection of the key Optiscan Imaging publications. For further publication enquiries, please contact


Acquisition and annotation in high resolution in vivo digital biopsy by confocal microscopy for diagnosis in oral precancer and cancer
Tami Yap, Ivy Tan, Rishi S. Ramani, Nirav Bhatia, Paula Demitrio de Souza Franca, Chris Angel, Caroline Moore, Thomas Reiner, Lindsay Bussau, Michael J. McCullough. 2023.

Dynamic real-time optical microscopy of oral mucosal lesions using confocal laser endomicroscopy
Camile S. Farah, Maya Janik, Sook-bin Woo, Jenny Grew, Zena Slim, Simon Fox. 2023.

Confocal microscopy in oral cancer and oral potentially malignant disorders: A systematic review
Rishi S. Ramani, Ivy Tan, Lindsay Bussau, Christopher M. Angel, Michael McCullough, Tami Yap. 2022.

A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer', European Journal of Nuclear Medicine and Molecular Imaging
Demétrio de Souza França, Paula, Susanne Kossatz, Christian Brand, Daniella Karassawa Zanoni, Sheryl Roberts, Navjot Guru, Dauren Adilbay, Audrey Mauguen, Cristina Valero Mayor, Wolfgang A. Weber, Heiko Schöder, Ronald A. Ghossein, Ian Ganly, Snehal G. Patel, and Thomas Reiner. 2021. 

Confocal endomicroscopy: a novel application for imaging of oral and oropharyngeal mucosa in human', European Archives of Oto-Rhino-Laryngology, 267: 443-48
Haxel, Boris Rainer, Martin Goetz, Ralf Kiesslich, and Jan Gosepath. 2010. 

Validation of the use of a fluorescent PARP1 inhibitor for the detection of oral, oropharyngeal and oesophageal epithelial cancers', Nature Biomedical Engineering, 4: 272-85
Kossatz, Susanne, Giacomo Pirovano, Paula Demétrio De Souza França, Arianna L. Strome, Sumsum P. Sunny, Daniella Karassawa Zanoni, Audrey Mauguen, Brandon Carney, Christian Brand, Veer Shah, Ravindra D. Ramanajinappa, Naveen Hedne, Praveen Birur, Smita Sihag, Ronald A. Ghossein, Mithat Gönen, Marshall Strome, Amritha Suresh, Daniela Molena, Ian Ganly, Moni A. Kuriakose, Snehal G. Patel, and Thomas Reiner. 2020. 

Systematic Intraoperative Application of Confocal Endomicroscopy for Early Detection and Resection of Squamous Cell Carcinoma of the Head and Neck: A Preliminary ReportIntraoperative Confocal Endomicroscopy for HNSCC', JAMA Otolaryngology–Head & Neck Surgery, 138: 404-11
Pogorzelski, Benjamin, Uli Hanenkamp, Martin Goetz, Ralf Kiesslich, and Jan Gosepath. 2012. 

Confocal fluorescence endomicroscopic imaging of the tongue (SPIE)
Zheng, Wei, Malini Olivo, K. W. Kho, Patricia Thong, Martin Harris, and Khee Chee Soo. 2005. 

May 24th, 2023 by Optiscan
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Intraoperative Confocal Laser Endomicroscopy: Prospective in Vivo Feasibility Study of a Clinical-Grade System for Brain Tumors." Journal of Neurosurgery  (01 Jul. 2022 2022): 1-11
Abramov, Irakliy, Marian T. Park, Evgenii Belykh, Alexander B. Dru, Yuan Xu, Timothy C. Gooldy, Lea Scherschinski, S. Harrison Farber, Andrew S. Little, Randall W. Porter, Kris A. Smith, Michael T. Lawton, Jennifer M. Eschbacher, and Mark C. Preul. 

Real-Time Intraoperative Surgical Telepathology Using Confocal Laser Endomicroscopy. Neurosurgical Focus 52, no. 6 (01 Jun. 2022 2022): E9
Abramov, Irakliy, Marian T. Park, Timothy C. Gooldy, Yuan Xu, Michael T. Lawton, Andrew S. Little, Randall W. Porter, Kris A. Smith, Jennifer M. Eschbacher, and Mark C. Preul. 

Progress in Confocal Laser Endomicroscopy for Neurosurgery and Technical Nuances for Brain Tumor Imaging with Fluorescein." Technology Report, Frontiers in Oncology 9, no. 554 (2019-July-03 2019)
Belykh, Evgenii, Eric J. Miller, Alessandro Carotenuto, Arpan A. Patel, Claudio Cavallo, Nikolay L. Martirosyan, Debbie R. Healey, Vadim A. Byvaltsev, Adrienne C. Scheck, Michael T. Lawton, Jennifer M. Eschbacher, Peter Nakaji, and Mark C. Preul. 

Confocal Laser Microscopy in Neurosurgery: State of the Art of Actual Clinical Applications." Journal of Clinical Medicine 10, no. 9 (2021): 2035
Restelli, Francesco, Bianca Pollo, Ignazio Gaspare Vetrano, Samuele Cabras, Morgan Broggi, Marco Schiariti, Jacopo Falco, Camilla de Laurentis, Gabriella Raccuia, Paolo Ferroli, and Francesco Acerbi. 

Characterization of Ex Vivo and in Vivo Intraoperative Neurosurgical Confocal Laser Endomicroscopy Imaging." Original Research, Frontiers in Oncology 12 (2022-August-24 2022)
Xu, Yuan, Irakliy Abramov, Evgenii Belykh, Giancarlo Mignucci-Jiménez, Marian T. Park, Jennifer M. Eschbacher, and Mark C. Preul. 

November 11th, 2022 by Optiscan
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General Surgery

Near-infrared confocal imaging during mini-laparoscopy: a novel rigid endomicroscope with increased imaging plane depth', J Hepatol, 53: 84-90
Goetz, M., I. Deris, M. Vieth, E. Murr, A. Hoffman, P. Delaney, P. R. Galle, M. F. Neurath, and R. Kiesslich. 2010.

In vivo confocal laser endomicroscopy of the human liver: a novel method for assessing liver microarchitecture in real time', Endoscopy, 40: 554-62
Goetz, M., R. Kiesslich, H. P. Dienes, U. Drebber, E. Murr, A. Hoffman, S. Kanzler, P. R. Galle, P. Delaney, and M. F. Neurath. 2008. 

A Pilot Study of the Feasibility of Confocal Endomicroscopy for Examination of the Human Airway', Journal of Bronchology & Interventional Pulmonology, 17: 126-30
Musani, A. I. M., M. M. Sims, C. M. Sareli, W. R. Russell, W. J. P. McLaren, P. M. B. H. Delaney, L. A. M. Litzky and R. A. J. M. Panettieri. 2010. 

November 10th, 2022 by Optiscan
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Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome', Gut: gutjnl-2021-325181
Bojarski, Christian, Paul Tangermann, Christian Barmeyer, Juliane Buchkremer, Ralf Kiesslich, Mark Ellrichmann, Stefan Schreiber, Carsten Schmidt, Andreas Stallmach, Robert Roehle, Christoph Loddenkemper, Severin Daum, Britta Siegmund, Michael Schumann, and Reiner Ullrich. 2021. 

In vivo endomicroscopy improves detection of Barrett's esophagus–related neoplasia: a multicenter international randomized controlled trial (with video)', Gastrointestinal Endoscopy, 79: 211-21
Canto, Marcia Irene, Sharmila Anandasabapathy, William Brugge, Gary W. Falk, Kerry B. Dunbar, Zhe Zhang, Kevin Woods, Jose Antonio Almario, Ursula Schell, John Goldblum, Anirban Maitra, Elizabeth Montgomery, and Ralf Kiesslich. 2014. 

In Vivo Confocal Endomicroscopy in the Diagnosis and Evaluation of Celiac Disease', Gastroenterology, 135: 1870-76
Leong, Rupert W. L., Nam Q. Nguyen, Christopher G. Meredith, Sam Al–Sohaily, Darko Kukic, Peter M. Delaney, Elise R. Murr, Jim Yong, Neil D. Merrett, and Andrew V. Biankin. 2008. 

Li, Wen-Bo, Xiu-Li Zuo, Chang-Qing Li, Fang Zuo, Xiao-Meng Gu, Tao Yu, Chuan-Lian Chu, Ting-Guo Zhang, and Yan-Qing Li. 2011. 'Diagnostic value of confocal laser endomicroscopy for gastric superficial cancerous lesions', Gut, 60: 299.

Mechanisms of Epithelial Cell Shedding in the Mammalian Intestine and Maintenance of Barrier Function', Annals of the New York Academy of Sciences, 1165: 135-42
Watson, Alastair J.M., Carrie A. Duckworth, Yanfang Guan, and Marshall H. Montrose. 2009. 

November 8th, 2022 by Optiscan
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